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临床试验/NCT00158119
NCT00158119已完成3 期

Ameliorating Disability Through Power Training

National Institute on Aging (NIA)1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2001年7月1日最近更新:
适应症

试验速览

阶段
3 期
状态
已完成
发起方
入组人数
160
试验地点
1
主要终点
Leg power

研究概览

简要总结

The purpose of this study is to evaluate two types of exercise therapy designed to improve muscle power and mobility: weighted vest exercise vs. progressive resistance training.

详细描述

Muscle power, a separate physical attribute from strength, is an important determinate of physical functioning in the elderly, for example in avoiding impending falls, rising from a chair, and climbing stairs. Muscle power, which declines with aging at a different rate than strength, has been shown in previous studies to improve through power training utilizing specially designed exercise equipment. However, weighted vest exercise could provide an acceptable, low cost, readily accessible alternative.

The hypotheses being tested in this study are: 1) weighted vest exercise will improve lower extremity power when compared to age matched controls in a standardized progressive resistance training program; 2) improvements in lower extremity power enhance functional performance as shown by improved gait velocity, stair climbing, and chair rise time; and 3) weighted vest exercise in impaired older adults will improve self-reported function and disability.

One hundred sixty-four men and women ages 65 and older, with some physical limitation but able to climb stairs independently, will be randomized to one of two 16-week exercise programs. The intervention group will participate in a weighted vest exercise protocol, consisting of chair-based and stair-climbing exercise, while the control group will participate in a standardized progressive resistance training program. Participants in both programs will meet three times per week for 30-60 minutes per session, for a total of 16 weeks, at a research exercise gym, and will be under the direct supervision of research staff.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Community dwelling men and women aged 65 or older
  • •Ability to provide informed consent
  • •Impairment in physical performance, based on a score between 4 and 10 inclusive on the SPPB (Short Physical Performance Battery), which evaluates standing balance, walking speed, and chair-rise time
  • •Score of 24 or greater on the Folstein mini-mental status exam
  • •Exhibit independent stair-climbing ability

排除标准

  • •Unstable acute or chronic disease
  • •Neuromusculoskeletal impairment interfering with independent stair climbing
  • •Abdominal aortic aneurysm
  • •Exertional angina
  • •History of ventricular arrhythmia
  • •Inguinal or abdominal hernia
  • •Symptomatic valvular heart disease

结局指标

主要结局

Leg power

leg strength

mobility

endurance

balance measured at baseline, 8 weeks, and 16 weeks

次要结局

  • Disability

研究者

发起方
National Institute on Aging (NIA)
申办方类型
Nih

研究点 (1)

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