Association of inflammatory markers with time to onset of spontaneous labor in preterm prelabor rupture of membrane
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To know levels of IL 6, hsCRP, procalcitonin in patients with preterm prelabor rupture of membrane
研究概览
简要总结
Patient with preterm prelabor rupture of membrane who are admitted in hospital willing to participate after counselling and fit into selection criteria will be recruited after obtaining written informed consent. Diagnosis of PPROM will be made by history of leaking and per-speculum examination. At admission routine antenatal workup, examination and investigations of all the enrolled patients will be done. Along with that blood samples for procalcitonin, IL 6, hsCRP will be collected and also at the time of onset of labor. Data will be recorded in pre-designed proforma. Results of IL6, hsCRP and procalcitonin will not be used for patient management. Management of the patients will be done as per hospital protocol
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- Female
入选标准
- •All hospitalized antenatal patients with preterm prelabor rupture of membrane with singleton pregnancy with gestational age between 28 weeks to 36 weeks + 6days.
排除标准
- •Patients with Pre-eclampsia Gestational Diabetes Multiple pregnancy Antepartum hemorrhage Intrauterine death Chorioamnionitis or any active infections Any known chronic inflammatory conditions.
结局指标
主要结局
To know levels of IL 6, hsCRP, procalcitonin in patients with preterm prelabor rupture of membrane
时间窗: Time to onset of labor from preterm prelabor rupture of membrane
次要结局
- Maternal and fetal morbidities
研究者
Dr BINDU BAJAJ
VMMC and Safdarjung Hospital New Delhi