2026-525608-85-00招募中3 期
The GranStone Trial - Prevention of Kidney Stones due to Paraffin Oil Induced Granuloma
Region Hovedstaden1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2026年7月1日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
研究概览
简要总结
The main objective is to determine whether treatment with empagliflozin or losartan can reduce the risk of kidney stones and disease progression in patients with paraffin induced granulomas.
入排标准
- 年龄范围
- 18 years 至 65+ years（18-64 Years, 65+ Years）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Signed informed consent by participant
- •18-70 years
- •Paraffin granuloma disease with hypercalcemia, hypoparathyroidism, hypercalciuria or a history of nephrolithiasis
排除标准
- •eGFR < 20 ml/min
- •Cancer (past or present, except basal cell skin cancer or squamous cell skin cancer), which in the investigator’s opinion could interfere with the results of the trial
- •Known autosomal dominant or autosomal recessive polycystic kidney disease, lupus nephritis or ANCA-associated vasculitis
- •History of organ transplantation
- •Receiving therapy with an SGLT2 inhibitor or ATII antagonist within 8 weeks prior to enrolment or previous intolerance of an SGLT2 inhibitor or ATII antagonist.
- •Known history of angioedema
- •Mental incapacity, language barriers or unwillingness to comply with the requirements of the protocol, which may preclude adequate understanding or co-operation during the trial, as judged by the investigator
研究者
Martin Blomberg Jensen
Scientific
Region Hovedstaden
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
Kidney stone Relief - A study of Trunapanchmuladi Ghrut in 80 adults (15-60 years).CTRI/2025/03/082881Dr VJD Gramin Ayurved Mahavidyalaya80
尚未招募
Unknown
Adding a New Sugar-Lowering Tablet to the Usual Kidney-Protective Medicine to Slow Kidney Damage in Adults from Tribal Areas of Gujarat”CTRI/2025/08/092448Dr Abhishek Bhalala130
尚未招募
不适用
Role of Dapagliflozin versus placebo in preventing kidney stone recurrenceCTRI/2025/12/098403Indian Council of Medical Research111
进行中（未招募）
1/2 期
To Investigate the Safety & Tolerability of HDCD-092330 in Healthy VolunteersCTRI/2024/04/065687Himalaya Wellness Company40
尚未招募
不适用
Homoepathic Management of Kidney Stones with Bryophyllum MothertinctureCTRI/2025/12/099121JIMS Homoeopathic medical college and hospital38