CTRI/2025/07/091429尚未招募3 期
Role of duloxetine in the prevention of chemotherapy induced peripheral neuropathy in patients recieving paclitaxel
Stanley medical College and hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年8月5日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To study the effect of duloxetine in the prevention of chemotherapy induced peripheral neuropathy in patients receiving paclitaxel
研究概览
简要总结
To study the effect of duloxetine in the prevention of chemotherapy induced peripheral neuropathy in patients receiving paclitaxel
To compare dose modification of paclitaxel due to peripheral neuropathy in each arm
20% dose reduction for grade I and II
discontinue drug for grade III and IV
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients recieving paclitaxel with any Cancer diagnosis with any stage will and able to comply with all study requirements with signed and written consent.
排除标准
- •Concurrent disease that may lead to peripheral neuropathy like diabetes mellitus rheumatologic disease vitamin B12 deficiency any allergy to duloxetine patients receiving ccb alfa blocker with psychiatric disorders any bleeding manifestations and pregnant and lactating women.
结局指标
主要结局
To study the effect of duloxetine in the prevention of chemotherapy induced peripheral neuropathy in patients receiving paclitaxel
时间窗: 12 WEEKS
次要结局
- To compare dose modification of paclitaxel due to peripheral neuropathy in each arm(3 months)
研究者
Navjot Kaur
Stanley medical College and hospital
研究点 (1)
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