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临床试验/NCT07705633
NCT07705633已完成不适用

Clinical Evaluation of Two Pit and Fissure Sealants Treated by Two Remineralizing Agents in Preventive Resin Restorations

Ismail Dahshan1 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2025年2月28日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
44
试验地点
1
主要终点
Retention rate of two types of pit and fissure sealants

研究概览

简要总结

The study aimed to assess the clinical evaluation of two different types of pit and fissure sealants after treating with two different remineralizing agents in preventive resin restorations.

Primary objectives:

Assessment of retention rate and marginal integrity of two types of pit and fissure sealants when using two types of remeneralizing agents using Ryge's criteria and Simonsen's criteria.

Secondary objectives:

Assessment of stability of results after 3, 6 and 9months.

详细描述

Dental caries is one of the most common intraoral diseases, with serious consequences for both the individual patient and for the public in terms of medical, social, and economic concerns. The individual patient suffers from pain, dysfunction of the oral system, and reduced quality of life.

Caries predominantly attack the occlusal surfaces of premolars and molars during their eruption . On the other hand, smooth surface caries have shown a significant decline, likely a result of increased worldwide access to fluoride . In previous reports, an incomplete post-eruptive maturation , and the presence of narrow and deep fissures were blamed for the increased caries susceptibility of occlusal surfaces . It has been more than 40 years since the pit and fissure sealants were first used clinically. During this time, pit and fissure sealants have been shown to be effective in reducing the risk of occlusal caries . A study aimed to evaluate the effect of the previous application of a casein phosphopeptide-amorphous calcium phosphate paste (MI Paste, MI) and adhesive systems on the bond durability of a fissure sealant. Ninety-eight enamel blocks were obtained from proximal surfaces of erupted third molars.

Anthor study evaluated the effect of treating the enamel with topical fluoride gel prior to acid etching on sealant retention clinically (Part I) and in vitro (Part II). Results showed no statistically significant differences between the test and control groups either clinically or in vitro. It is concluded that topical fluoride application prior to acid etching does not have a deleterious effect on sealant retention .

The study aimed to assess the clinical evaluation of two different types of pit and fissure sealants after treating with two different remineralizing agents in preventive resin restorations.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
15 Years 至 40 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Absence of restorations or prior sealants on the teeth under study.
  • Patients have simple occlusal spot caries lesions
  • Age group 15 - 40 years.
  • Ability to return for periodic follow-up

排除标准

  • Patients with high DMFS.
  • Any fixed orthodontic appliances.
  • Smoking habit.
  • Pregnant and lactating mothers
  • Symptoms of dental pain

结局指标

主要结局

Retention rate of two types of pit and fissure sealants

时间窗: After 3 months, 6 months and 9 months

Assessment of retention rate of two types of pit and fissure sealants when using two types of remeneralizing agents using Ryge's criteria

次要结局

  • marginal integrity assessments(After 3 months, 6 months and 9 months.)

研究者

发起方
Ismail Dahshan
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Ismail Dahshan

Resident

Suez Canal University

研究点 (1)

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