The Effect of Information Processing Speed on Motor Function, Balance, Gait, and Quality of Life in Patients With Ischemic Stroke
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Symbol Digit Modalities Test (SDMT) Score
研究概览
简要总结
Stroke rehabilitation programs are traditionally designed based on the evaluation of motor and sensory impairments starting from the acute phase. Although studies in diseases such as multiple sclerosis and Parkinson's disease have shown that information processing speed may affect motor function and balance, no such study has been conducted in stroke patients.
This study aims to investigate the effect of information processing speed on motor function, balance, gait, and quality of life in patients with ischemic stroke.
详细描述
A review of the literature reveals that in stroke patients, motor and sensory impairments are evaluated beginning in the acute phase, and rehabilitation programs are structured accordingly. While research has demonstrated that information processing speed can influence motor function and balance in other neurological conditions such as multiple sclerosis and Parkinson's disease, no similar studies exist for stroke populations.
The investigators hypothesize that early evaluation of motor, sensory, and cognitive deficits in patients with ischemic stroke, and incorporating these findings into rehabilitation programs, may positively impact prognosis.
This study will recruit patients admitted for treatment at the Physical Medicine and Rehabilitation Unit of Istanbul Aydın University VM Medical Park Florya Hospital. Inclusion criteria are: age ≥ 40 years, first-ever ischemic stroke, hemodynamic stability, literacy, and absence of pre-stroke psychiatric, neurological, visual, auditory, or orthopedic conditions that may affect mobilization. Additionally, patients must score full points in the vision and speech domains of the NIHSS after stroke.
Eligible participants' demographic and clinical data will be recorded. Information processing speed will be assessed using the Symbol Digit Modalities Test (SDMT). Motor function will be evaluated with the Fugl-Meyer Assessment (FMA), balance with the Berg Balance Scale (BBS) and the Sense4Motion Euleria Health device, gait with the Timed Up and Go Test (TUG), and quality of life with the Stroke-Specific Quality of Life Scale (SS-QOL).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 40 years or older
- •First-ever ischemic stroke
- •Hemodynamically stable
- •Able to read and write (literate)
- •No history of psychiatric, neurological, visual, auditory, or orthopedic conditions prior to stroke that could affect mobilization
- •After stroke, full scores in the vision and speech domains according to the NIH Stroke Scale (NIHSS)
排除标准
- •Recurrent stroke
- •Post-stroke visual or hearing impairment
- •Conditions causing impaired consciousness such as dementia, confusion, or delirium
- •Presence of cardiovascular or orthopedic conditions after stroke that prevent mobilization
- •Age 75 years or older
结局指标
主要结局
Symbol Digit Modalities Test (SDMT) Score
时间窗: At baseline (single assessment)
The Symbol Digit Modalities Test (SDMT) will be used to assess information processing speed. The test requires participants to match symbols with corresponding numbers according to a reference key within 90 seconds. The total number of correct responses will be recorded, with higher scores indicating better processing speed.
次要结局
- Berg Balance Scale (BBS) Score(At baseline (single assessment))
- Fugl-Meyer Assessment (FMA) Score(At baseline (single assessment))
- Stroke-Specific Quality of Life Scale (SS-QOL) Score(At baseline (single assessment))
- Balance Assessment with Sense4Motion Euleria Health / Euleria Lab Device(At baseline (single assessment))
- Timed Up and Go Test (TUG) with Euleria Health / Euleria Lab(At baseline (single assessment))
研究者
Dudu Kübra AKYOL
Principal Investigator
Istanbul Aydın University