ACTRN12614000300673招募中未知
The effect of bisphosphonate therapy on the human immune system
Bone Research Group, Garvan Institute of Medical Research0 个研究点目标入组 44 人开始时间: 2014年3月20日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 44
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20 Years 至 o limit（—）
- 性别
- All
入选标准
- •Sex: male or female
- •Age range: 20 years of age or older
- •Disease status: diagnosis of osteoporosis based on either a T-score of less than or equal to -2.5 SD on bone densitometry or minimal trauma fracture.
- •Must meet the PBS authority criteria for bisphosphonate therapy.
- •Concomitant disease status: immunocompetent
- •Laboratory parameters: eGFR equal to or more than 30
- •Willingness to give written or informed consent and willingness to participate to and comply with the study.
排除标准
- •Women lactating, pregnant or of childbearing potential who are not willing to avoid becoming pregnant during the study.
- •Laboratory parameters: eGFR < 30
- •Patients who have received previous anti-resorptive therapy.
- •Patients with dental issues requiring extraction or intervention involving the jaw bone.
- •Patients unable to give informed consent.
- •Patients receiving medication that may interact with either prenylation or the immune system: statin therapy and immunosuppressant therapy including glucocorticoids
研究者
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