Dose-Dependent INhibitory Effect of RosuVastatin In Japanese PatienTs with Acute Myocardial InfarcTION on Serum Concentration of Matrix Metalloproteinases - INVITATION Trial

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University0 个研究点目标入组 120 人开始时间: 2015年4月1日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•Patients meeting the following criteria will be excluded from the study: 1)Administered statin within three month at the registration 2)Severe hypertension (SBP>=180 mmHg or DBP>=110 mmHg) 3)Familial hypercholesterolemia 4)Serum triglyceride level>=400 mg/dL 5)Prior onset of cardiovascular or cerebrovascular disease within 6 months before registration of this study 6)Hypersensitivity to statins 7)History of drug-induced myopathy 8)Active liver disease or elevated liver enzymes (ALT or AST > 3 times upper limit of normal [ULN], or bilirubin > 2 times ULN) 9)Nephrotic syndrome or renal dysfunction (creatinine clearance <30 mL/min/1.73 m2 or serum creatinine >2.0 mg/dL) 10)Administered cyclosporin 11)Serious concurrent disease such as malignancy, or patients with severely limited lifespan 12)Pregnant 13)Judged by the investigators to be ineligible for participation in the study for any other reason

发起方

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University