Single arm clinical trial to evaluate the efficacy of oral administration of Chitrakadi Kwatha in the management of Prathama-Dwitiya Patalagata Timira with reference to myopia.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Symptoms like Avakatmekshateroopam (visual hallucination), Vyaktamapyanimitta (transient nature of bluriness), Dooramnekshate (difficulty of distant vision) will be decreased and relief from myopia.
研究概览
简要总结
The visual disturbance is represented as one of the complex problem in the field of ophthalmology. Myopia is refractive error in which parallel rays of light from an infinity enters the eye and is focused in front of retina, when accommodation is at rest. The progress of the disease myopia causes gradual loss of vision and sometime it causes severe visual impairment. In modern science the treatment for myopia is use of eyeglasses, contact lens, laser assisted in situ keratomileusis(LASIK), laser-assisted sub epithelial keratectomy(LASEK), refractive keratometry. In Ayurveda, when the vitiated Doshas invades Patala, the patient complains about the symptoms of disease i.e. difficulty to see distant object or blurred vision. etc. and if untreated it shifts to next Patala. But according to Ayurvedic Samhita, Prathama-Dwitiya Patalagata Timira is Aushdha Sadhya Vyadhi. modern techniques i.e. refractive surgeries for treatment for myopia are costly hence the Ayurvedic science is better alternative for this condition. The oral administration of Chitrakadi Kwatha is an easy and feasible procedure. It is also affordable to patient. It prevents pathology of Timira. Dravyas includes in yoga includes are Chitrakmula, Triphala, Patol, Yava and Ghrita. Oral administration of Chitrakadi Kwatha which is said by Acharya Vangasen is selected for study. Purpose of study is found out solution for Prathama Dwitiya Patalagata Timira
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient Enrolled with symptoms of Prathama-Dwitiya Patalagata Timira i.e. Avakatmekshateroopam (visual hallucination), Vyaktamapyanimitta (transient nature of blurriness), Dooramnekshate (difficulty of distant vision) in Shalakya OPD.
- •Age-18 to 40 years.
- •Patient who have <-3D refractive index in the eyes.
- •Patient of either gender.
- •Patient having visual acuity of 6/12, 6/18, 6/24, 6/36, 6/60, or less than 6/60 in the eyes.
- •Patient who ready to give consent.
排除标准
- •Patient who have symptoms of Tritiya and Chaturtha Patalagata Timira will be excluded.
- •Congenital type of myopia, pathological type of myopia, acquired or secondary type of myopia that occurs due to some factors or diseases i.e. post traumatic, drug induced, post keratitis.
- •will be excluded.
- •Myopia associated with other ocular diseases like cataract, glaucoma, etc.
- •Patient who have myopia associated with other refractive errors such as astigmatism, presbyopia.
- •Patient who have known case of hypertension, diabetes mellitus, Rheumatic arthritis or any other arthritic conditions, rheumatic heart disease, thyroid disorder, asthma, Koch’s, HIV will be excluded.
- •Patient who have active infectious diseases i.e. viral, fungal, bacterial conjunctivitis, trachoma, blepharitis.
- •Patient below 18 years and above 40 years will be excluded.
结局指标
主要结局
Symptoms like Avakatmekshateroopam (visual hallucination), Vyaktamapyanimitta (transient nature of bluriness), Dooramnekshate (difficulty of distant vision) will be decreased and relief from myopia.
时间窗: Follow of will be taken on 7th, 15th day and symptoms will be noted of before and after treatment.
次要结局
- Improvement in visual acuity of patient, decrease in severity and duration of symptoms(18months.)