NCT02806479已完成不适用
Pilot Observational Case-control Study of the Electrical Heterogeneity in Patients With Hypertrophic Cardiomyopathy and High Arrhythmic Risk
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Non-invasively reconstructed epicardial activation map
研究概览
简要总结
This study evaluates mechanisms of arrhythmogenicity in hypertrophic cardiomyopathy, in comparison to patients with well-understood arrhythmogenic substrate (ischemic cardiomyopathy), as well as to individuals free from arrhythmogenic substrate
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed HCM
- •Documented history of sustained ventricular tachyarrhythmia or resuscitated sudden cardiac arrest
- •Maximal left ventricular wall thickness of > 30mm
- •Extensive fibrosis on cardiac MRI (>15% of total myocardial volume)
- •>7.5%/5-year risk of sudden cardiac death as determined by HCM risk-SCD
排除标准
- •age < 18 years
- •Pregnancy
- •Atrial Fibrillation
结局指标
主要结局
Non-invasively reconstructed epicardial activation map
时间窗: within one day
次要结局
未报告次要终点
研究者
Larisa Tereshchenko
Assistant Professor
Oregon Health and Science University
研究点 (1)
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