Uppföljning av Patienter Som intensivvårdats för COVID-19
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Anxiety
研究概览
简要总结
The study will follow COVID-19 patients who required intensive care after 3-6 months and one year after discharge from the ICU with functional level as well as organ function to assess recovery after COVID-19. Blood and urine will be collected for biobanking.
详细描述
The study will follow COVID-19 patients who required intensive care at Uppsala University Hospital and were included in the Uppsala COVID-19 biobank. The patients will be contacted after three to six months for a first follow-up with assessment of functional level in activities of daily life, psychiatric symptoms, neurological symptoms and working capacity as well as specific organ functions. The organ functions will include circulation, respiration, coagulation, immune function and kidney function. In addition, blood and urine will be collected for biobanking.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •PCR-verified Covid-19
- •Treated in ICU
排除标准
- •Pregnant of breastfeeding
结局指标
主要结局
Anxiety
时间窗: Three to six months from discharge from ICU
Screening for anxiety using the Generalised Anxiety Disorder 7-item scale.
Mortality
时间窗: Within 1 year after admission to ICU.
Death
Renal recovery
时间窗: At follow-up one year after ICU discharge.
Return of renal function measured as CKD stage.
Frailty
时间窗: Three to six months from discharge from ICU
Screening for frailty using the Clinical Frailty Scale-9.
Quality of life score
时间窗: Three to six months from discharge from ICU
Quality of Life assessed using the 36-item short form survey by RAND.
Activities of Daily Life
时间窗: Three to six months from discharge from ICU
Screening of functional level for Activities of Daily Life using the 5-level EQ-5D.
Neurological recovery
时间窗: Three to six months from discharge from ICU
Neurological function as assessed by a clinician
Respiratory recovery
时间窗: Three to six months from discharge from ICU
Respiratory function as assessed by a clinician
Working capacity
时间窗: Three to six months from discharge from ICU
6 min walk test
Cognitive recovery
时间窗: Three to six months from discharge from ICU
Cognitive screening using the Montreal Cognitive Assessment.
Depression
时间窗: Three to six months from discharge from ICU
Screening for depression using the Patient Health Questionnaire 9.
次要结局
未报告次要终点