A Study of Therapeutic Efficacy of Categorical Language Fluency Smartphone Game Application in Mild Cognitive Impairment and Mild Alzheimer's Dementia (Baseline Study)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 主要终点
- Application usage log
研究概览
简要总结
The purpose of this study is to examine therapeutic efficacy of categorical language fluency smartphone game application in mild cognitive impairment and mild Alzheimer's dementia.
详细描述
The Categorical Language Fluency Smartphone Game Application was developed based on the semantic distance training, which was effective in improving categorical language fluency of mild cognitive impairment and mild Alzheimer's dementia. 10 patients with mild cognitive impairment and another 10 patients with mild Alzheimer's dementia were recruited to examine therapeutic efficacy of the application.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged above 55
- •Confirmed literacy
- •Diagnosed to mild cognitive impairment by International Working Group on Mild Cognitive Impairment and Clinical Dementia Rating(CDR) of 0 or 0.
- •Diagnosed to possible or probable Alzheimer's dementia by NINCDS-ADRDA and Clinical Dementia Rating(CDR) of 1 or below.
排除标准
- •Evidence of delirium, confusion
- •Any neurological conditions causing cognitive decline such as Parkinson's disease, brain hemorrhage, brain tumor, normal pressure hydrocephalus
- •Evidence of severe cerebrovascular pathology
- •History of loss-of-consciousness over 1 hour due to head trauma or repetitive head trauma of mild severity
- •History of substance abuse or dependence such as alcohol
- •Presence of depressive symptoms that could influence cognitive function
- •Presence of medical comorbidities that could result in cognitive decline
研究组 & 干预措施
Categorical Language Fluency Smartphone Application
Smartphone game application specifically aimed at training categorical language fluency
干预措施: Categorical Language Fluency Smartphone Application (Device)
结局指标
主要结局
Application usage log
时间窗: 4-weeks treatment
Log to assess compliance of participant(by describing frequency and duration of training by using application)
次要结局
- Subjective Memory Complaint Questionnaire(after 4-weeks treatment)
- Geriatric Depression Scale(after 4-weeks treatment)
- Korean version of MMSE for dementia screening(after 4-weeks treatment)
研究者
Ki Woong Kim
Professor, department of neuropsychiatry
Seoul National University Bundang Hospital