EUCTR2007-005679-33-DE进行中（未招募）1 期
Influence of the selective endothelin receptor-blocker Ambrisetan on the portal pressure in patients with cirrhosis - ADAPT-Studie
Medizinische Fakultät der Martin-Luther-Universität Halle-Wittenberg0 个研究点开始时间: 2010年10月4日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Histologically/ laboratory or sonographically confirmed diagnosis of hepatic cirrhosis
- •- Compensated hepatic disease (Child A and B)
- •- Portal hypertension
- •- Age: 18 - 75
- •- Signed, written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 24
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 24
排除标准
- •- Acute infection
- •- Hepatic encephalopathy Stadium II- IV
- •- Alcoholic hepatitis and other acute manifestations of hepatitis
- •- Pylethrombosis
- •- Transaminases increased > 3 x UNL
- •- Advanced stadium of cardiac and/or pulmonary preventing head-down position
- •- Evidence of known advanced malignant disease
- •- Usage of beta-blockers within the last 72 hours
- •- Pregnancy or lactation
- •- Participation in another clinical trial
- •- Marked hypotension (systolic blood pressure less than 90 mmHg )
- •- Advanced hepatic disease (stadium Child C)
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