Idiopathic non-cirrhotic intrahepatic portal hypertension (INCIPH): assessment of thrombophilia and histopathology in a multicentre cohort study and HIV patients. - Idiopathic non-cirrhotic intrahepatic portal hypertension (INCIPH)

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 50 人开始时间: 待定最近更新: 2024年5月6日

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•1) Evidence of portal hypertension (oesophageal varices, hypersplenism or ascites)
•2) Doppler ultrasound showing patent portal and hepatic veins
•3) Liver biopsy showing no cirrhosis
•4) Exclusion of conditions causing cirrhosis according to conventional diagnostic criteria (chronic viral hepatitis, alcoholic liver disease, NASH, obesity, hemochromatosis, autoimmune hepatitis or Wilson*s disease)
•5) Exclusion of chronic vitam A intake, professional exposure to copper sulphate, vinyl chloride monomer, Spanish toxic oil or arsenic salts
•6) Older than 18 years at diagnosis.
•7) HIV patients

•1) Presence of cirrhosis
•2) Presence of portal thrombosis at diagnosis
•3) Presence of conditions causing cirrhosis according to conventional diagnostic criteria (chronic viral hepatitis, alcoholic liver disease, NASH, obesity, hemochromatosis, autoimmune hepatitis or Wilson*s disease).
•4) Presence of chronic vitam A intake, professional exposure to copper sulphate, vinyl chloride monomer, Spanish toxic oil or arsenic salts
•5) Younger than 18 years old at diagnosis.
•6) intake oral anticoagulation

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