Noise, Oxidative Stress and Cardiovascular System
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Systolic blood pressure
研究概览
简要总结
Environmental noise represents a health problem for at least one in five citizens of the European Union. Noise exposure leads to the development of arterial hypertension, myocardial infarction, stroke, and obesity. Given the limited information on noise exposure and noise effects on humans in the Republic of Serbia, the overall objective of NOXYCARD is to collect environmental noise levels data; to identify long-term and short-term noise effects on the cardiovascular system; and to evaluate the levels of blood stress hormones, oxidative stress, and inflammation in individuals with normal body weight and individuals with obesity.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18-65
- •both genders
- •good self-reported health
排除标准
- •diabetes mellitus
- •arterial hypertension or other cardiovascular diseases
- •kidney diseases
- •pregnancy
- •malignant diseases
- •mental diseases
结局指标
主要结局
Systolic blood pressure
时间窗: 10, 40, and 50 minutes
Systolic blood pressure in mmHg, higher values indicate high risk
Concentration of stress hormone
时间窗: 10, 40, and 50 minutes
Cortisol level in mcg/dL, higher values indicate high risk
次要结局
- Concentration of inflammation parameters(10, 40, and 50 minutes)
- Diastolic blood pressure(10, 40, and 50 minutes)
研究者
Katarina Paunovic
Professor
University of Belgrade