CODP Imaging From a Dose Perspective - Effective Organ Doses of a Combined Inspiration-expiration Protocol on a 3rd Generation Dual-source CT
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,957
- 主要终点
- organ specific radiation doses
研究概览
简要总结
The noncontrast-enhanced chest computed tomography (CT) is an emerging diagnostical tool in patient with chronic obstructive pulmonary disease (COPD). As shown in previous studies and pointed out by the Fleischner society, an additional scan in expiration reflects the pathophysiology of this complex disease better and extends the clinical information of the CT.
Nevertheless, this scan is leading to an increase in radiation dose. But currently it is unclear if this increased radiation dose is proportional to the additional clinical value when compared to inspiration-only protocols. Therefore, the aim of this study was to compare the organ specific radiation doses of a combined inspiration-expiration CT on a 3rd generation dual-source scanner with noncontrast-enhanced chest CTs of two clinical routine scanners. Therefore, the radiation doses of nearly 2000 chest CTs have been evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •noncontrast-enhanced chest CT performed on one of the named devices
- •imaging performed between August 2014 and September 2017
- •CT protocol used as previously specified
排除标准
- 未提供
结局指标
主要结局
organ specific radiation doses
时间窗: The organ dose calculations have been performed retrospectively. Therefore, the time frame is variable. The time set for the final outcome calculations was September 2017. Therefore, the time frame varies between 3 years and 1 week.
Organ specific radiation doses of 17 individual organs
次要结局
未报告次要终点
研究者
Joshua Gawlitza
Head of COPD imaging research
Universitätsmedizin Mannheim
