NCT00169689已完成不适用
Therapeutic and Biological Effects of High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Schizophrenia
Heinrich-Heine University, Duesseldorf2 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2003年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Clinical Global Impression;
研究概览
简要总结
The study is a prospective, randomized, double-blind sham-controlled study.
详细描述
The principal objective of this trial is to investigate the effect of left prefrontal high frequency rTMS on negative symptoms in schizophrenia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •DSM-IV criteria for schizophrenia
- •age between 18 and 60
- •informed consent
- •right handed patient
- •no change of antipsychotic treatment > 2 weeks before recruitment
排除标准
- •seizures, epilepsy
- •history of severe head injury
- •status post implantation of a cardiac pacemaker or other electronic devi-ses
结局指标
主要结局
Clinical Global Impression;
时间窗: November 2007
次要结局
- Global psychosocial functioning (GAF), PANSS-Negative Subscale,changes in EEG, heart rate variability, cortisol daytime profile, catecholamines, cognitive functioning(November 2007)
研究者
研究点 (2)
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