Developing Pharmacist-led Research to Educate and Sensitive Community Residents to the Inappropriate Prescription Burden in the Elderly
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 600
- 主要终点
- Complete discontinuation of inappropriate prescriptions.
研究概览
简要总结
The objective of this trial is to test the beneficial effect of a pharmacist-initiated knowledge transfer intervention to both patients and prescribers on the discontinuation of inappropriate prescriptions, compared to usual care. The investigators hypothesize that the pharmacist-led intervention will reduce inappropriate prescriptions by at least 20% over 6-months compared to usual care. The intervention consists of simultaneously educating consumers and providing physicians with an evidence-based pharmaceutical opinion on inappropriate prescriptions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women 65 years of age and older (no upper age limit)
- •Individuals for whom prescription claims derive from only one pharmacy identifier
- •Chronic consumption (> 3 month claims) of one of the target inappropriate prescriptions. (benzodiazepine/non benzodiazepine hypnotic, long-acting sulfonylurea oral hypoglycemic agents, anticholinergic agents (in the form of first-generation antihistamines) or Nonsteroidal anti-inflammatory drugs [NSAIDs] )
- •Patients who are willing to participate in the study.
排除标准
- •A probable diagnosis of dementia (persons without the capacity to provide informed consent), as determined by a) a prescription for memantine or a cholinesterase inhibitor; b) report from a caregiver or family-member; or c) a baseline screening score on the Folstein Mini-Mental State Exam < 24
- •Inability to understand and or communicate in English and/or French
- •Patients living in a long-term care facility
- •Concomitant use of any antipsychotic medication
研究组 & 干预措施
Pharmacist-led educational intervention
Participants will receive an educational brochure on an inappropriate prescription they are currently taking from their pharmacists. Participants' physicians will receive an evidence-based pharmaceutical opinion for the same medication.
干预措施: Pharmacist-led educational intervention (Behavioral)
Control
Participants in the control group will be wait-listed and observed for 6 months prior to receiving the intervention.
结局指标
主要结局
Complete discontinuation of inappropriate prescriptions.
时间窗: 6 months
Provincial prescription insurance claims will be used to measure whether the inappropriate prescription has been discontinued in the intervention and control group at 6-months. Prescription data contain information on all dispensed prescriptions including drug name, dispensation date, dosage, drug form, duration and quantity of the drug dispensed, as well as the license number of the physician who wrote the prescription. Discontinuation of an inappropriate prescription will be defined as the lack of a claims renewal for that medication during a minimum of three or more consecutive months (with no subsequent renewals) during the nine months following receipt of the intervention.
次要结局
- The frequency, timing and type of pharmaceutical opinions sent by the pharmacist to the patient's primary care physician.(6 months)
- Effect of the pharmaceutical opinion on the prescriber's behaviour.(6 months)
- Patient-physician encounters to discuss inappropriate prescriptions.(6 months)
研究者
Cara Tannenbaum
Dr. Cara Tannenbaum
Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal