跳至主要内容
临床试验/NCT00743691
NCT00743691已完成不适用

Impact of Strengthened Health Extension Program and Community Based Treatment of Neonatal Infections on Neonatal Mortality in Oromia and South Nation and Nationalities & People Region(SNNPR), Ethiopia

Save the Children1 个研究点 分布在 1 个国家目标入组 19,476 人开始时间: 2009年6月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
19,476
试验地点
1
主要终点
All cause Neonatal Mortality

研究概览

简要总结

The purpose of the study is to determine whether community based management of infections with antibiotics administered by health extension workers reduce all cause mortality in neonates after the first day of life compared to current MOH IMNCI model of referral to hospital

详细描述

Although 44% of neonatal deaths in Ethiopia are due to infection, access to treatment for neonatal infections is very low for most families. Even though the newly adapted Integrated Management of Newborn and Childhood Illness (IMNCI) package includes assessment of newborns, if a baby has any danger signs that may be suggestive of infection and is taken to health posts, the baby is to be referred to hospital for treatment. Given that only about 5% of neonatal deaths occur in hospitals and the distance to hospital is often far and the costs prohibitive, very few babies are likely to receive essential lifesaving antibiotics. Evidence from India, Bangladesh, and Nepal demonstrates that community health workers can effectively manage neonatal infections at home. However it is not known whether and community-based management of neonatal infections is effective, feasible and acceptable in the Ethiopian context. Local evidence regarding lives saved and cost is required in order to inform health policy and programming regarding community-based treatment of neonatal infections.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
1 Minute 至 4 Weeks(Child)
性别
All
接受健康志愿者

入选标准

  • Participants who give consent to be treated at Health Post by Health extension worker

排除标准

  • If Newborn is Critically sick

研究组 & 干预措施

Arm1

No Intervention

Make a diagnosis of Neonatal infections and refer patients according to IMNCI guideline

2

Active Comparator

Health extension Workers will Make a diagnosis of Neonatal infections and treat with antibiotics when referal is not possible

干预措施: Community Based (Other)

结局指标

主要结局

All cause Neonatal Mortality

时间窗: 2 years

次要结局

  • Additional cost for community based neonatal infection management(2 years)
  • Adding identification and treatment of newborns and children to the package of services provided by HEWs/CHPs will not adversely affect the coverage of other services currently provided.(2 years)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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