A Feasibility Randomised Controlled Trial to compare REgional versus General Anaesthesia in Reducing Delirium in patients with Hip Fractures

niversity of Warwick0 个研究点目标入组 100 人开始时间: 2017年10月12日最近更新: 2021年6月14日

试验速览

暂无简介。

•1. Clinically or radiographically diagnosed intracapsular or extracapsular hip fracture
•2. Planned surgical treatment via hemiarthroplasty, total hip arthroplasty or appropriate fixation procedure
•3. Aged 65 years and over

•1. Multiple trauma or planned concurrent surgery not amenable to spinal anaesthesia
•2. Absolute contraindication to regional anaesthesia:
•2.1. Known or suspected congenital or acquired coagulopathy
•2.2. Active use of pharmacological anticoagulants within a timeframe defined to contraindicate neuraxial block placement
•2.3. Known or suspected unrepaired critical or severe aortic stenosis
•2.4. Known or suspected active skin infection at the planned needle insertion site
•2.5. Known or suspected elevated intracranial pressure contraindicating dural puncture; previous spinal surgery precluding RA, localised sepsis in lumbar spine, documented allergies to local anaesthetic
•3. Known or suspected to be at elevated risk for malignant hyperthermia
•4. Previous participation in the REGARD trial
•5. Determination by the surgeon or the anaesthetist that the patient would not be suitable for randomisation
•6. Patient not expected to survive beyond 48 hours

发起方

niversity of Warwick