A study to determine the aetiology of Infectious Spondylodiscitis and todevelop a diagnostic scoring system
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Will determine the aetiology of the infectious spondylodiscitis
研究概览
简要总结
Spondylodiscitis is an infectious inflammation that affects vertebral discs and adjacent
structures. It is induced by a broad spectrum of pathogens, including both tubercular and
bacterial infections such as Brucella spp., Staphylococcus spp., Streptococcus spp., and
Enterobacteriaceae. Infectious spondylodiscitis (IS) is a condition that presents a diagnostic
dilemma and mandates prolonged treatment. It has been diagnosed with alarming frequency
over the past decade. Data from a United Kingdom (UK) census shows a 150% increased
incidence of IS in the past decade compared to the previous decades(1). This could reflect the
increased number of invasive spinal procedures in the recent past and the expansion in the
elderly and immunocompromised population as well. Early diagnosis and treatment become
crucial as the disease can have potentially irreversible neurologic consequences. Despite this
disease’s increased incidence and prevalence in India, the diagnosis is usually delayed in most
of these cases. Hence this study is designed to develop a diagnostic algorithm for infectious
spondylodiscitis.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who were confirmed to have infectious involvement in the spine
- •Patients with a microbiologically confirmed diagnosis and an MRI image taken at the time of diagnosis.
排除标准
- •Postoperative spine infections or infections related to implants.
结局指标
主要结局
Will determine the aetiology of the infectious spondylodiscitis
时间窗: 1 year
次要结局
- Generate a diagnostic scoring algorithm for the infectious Spondylodiscitis(1 year)