NCT00533754Unknown不适用
Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population
Rudolf Foundation Clinic2 个研究点 分布在 1 个国家开始时间: 2006年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 试验地点
- 2
- 主要终点
- higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals
研究概览
简要总结
The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals.
Additionaly a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •man and women over 18 years old
- •Filled out informed consentBereitschaft zur Teilnahme
- •Diagnosis of non-exudative/ exudative age related macular dgeneneration
排除标准
- •inherited retinal diseases
- •other aquired retinal/ macular
- •missing informed consent
结局指标
主要结局
higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals
次要结局
- a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD
研究者
研究点 (2)
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