Comparing effect of 6% hydroxyethyl starch-450 Versus ringer lactate on Blood sugar levels during lower limb surgery under subarachnoid block: A prospective randomised interventional study in Department of Anaesthesia, SMS medical college, jaipur
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Mean Blood sugar level
研究概览
简要总结
Hypotensionafter spinal anesthesia remains a major clinical problem. Administration of intravenous fluid is one of the most commoninterventions in medicine [1].
Fluid resuscitation forhypovolemic shock is an integral part of acute medical management in theIntensive Care Unit (ICU) and Operation Theatre (OT) and in the emergencydepartment. Colloids and crystalloids are also used as co-loading fluids tolimit complications like hypotension following sympathetic blockade in thecentral neuroaxial blockade [2].
Ringerlactate, a balanced salt solution is the most common crystalloid fluid used forfluid resuscitation. It is also preferred as the fluid of choice for co-loadingin patients following SAB. Commercially available colloids are widelyrecommended in several resuscitation guidelines and intensive care algorithms [3& 4].
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing elective surgery of lower limb under subarachnoid block.
- •Non diabetic Patients
- •BMI<30 Kg/m2.
排除标准
- •1.Diabetic patients 2.Patients on regular use of steroid 3.Patients on regular use of ascorbic acid 4.Patients having low hematocrit [ pcv <30% ] 5.Pregnancy 6.Chronic kidney and liver diseases 7.Any cardiac disease or coagulation disorders 8.Surgery taking more than 3 hrs 9.Any Addiction (alcohol and drugs abusers).
结局指标
主要结局
Mean Blood sugar level
时间窗: At 15 min | At 30 min | At 45 min | At 60 min | At 120 min | At 150 min
次要结局
- Mean Heart rate(Mean Systolic blood pressure , Mean diastolic blood pressure, Mean arterial blood pressure)