NCT07305922招募中不适用
Delayed Cerebral Infarction Beyond Endoluminal Spasmolysis and Induced Hypertension
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Mean Flow Velocity (MFV)
研究概览
简要总结
An observational study of patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage, employing multimodal neuromonitoring.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults 18 years or older
- •Critical care after subarachnoid haemorrhage
- •Aneurysm secured by surgical clipping or endovascular procedure
- •Suspected, emerging or established severe cerebral vasospasm
排除标准
- •Anticipated survival less than five days, as determined by treating clinician
- •Transcranial Doppler signal too weak
- •Pregnancy
研究组 & 干预措施
Patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage
干预措施: Induced hypertension with norepinephrine (Drug)
Patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage
干预措施: Endoluminal Spasmolysis (Drug)
结局指标
主要结局
Mean Flow Velocity (MFV)
时间窗: Up to 12 hours post intervention
Increase or decrease of Mean Flow Velocity of the medial cerebral artery as determined by Transcranial Doppler.
次要结局
- Duration of MFV change after Endoluminal Spasmolysis(Up to 12 hours)
研究者
Peter Rudberg
Senior Consultant, Research Group Leader
Karolinska Institutet
研究点 (1)
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