Postoperative Respiratory Monitoring After Neuraxial Opioid Administration for Cesarean Delivery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- CO2 monitoring
研究概览
简要总结
Respiratory depression occurs in labor and delivery; noticeably when neuraxial opioids are given.Pathophysiological respiratory depression -failure to respond to hypercapnia or hypoxia - is challenging to measure clinically.American Society of Anesthesiologist guidelines recommend suitable respiratory monitoring for 24 hours post cesarean delivery (CD).
Use of capnograph will enable us to assess breath-by-breathe respiration in a population receiving neuraxial opioids - potentially at risk for respiratory depression.
Our aim is to assess our ability to capture maternal postpartum respiratory parameters in a cohort following opioid neuraxial administration for CD.
详细描述
The investigators wish to test the efficacy of capnograph in detection of apnea and respiratory depression in women following cesarean delivery. Currently, routine intensive monitoring such as the investigators propose is not performed, and many apneas may go undetected.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •American Society of Anesthesiologists physical status class I or II
- •Age between 18 and 45
- •Gestational age greater than 37 completed weeks
- •Singleton pregnancy.
排除标准
- •Contraindication for neuraxial analgesia (bleeding diathesis, neuropathy, severe scoliosis, previous spine surgery, local anesthetic allergy)
- •Allergies to postoperative medication (opioids, NSAIDs, acetaminophen)
- •Chronic opioid use
- •Opioid administration in the previous 12 hours
- •Inability to adequately understand the consent form
- •Blocked nose or nasal deformity.
结局指标
主要结局
CO2 monitoring
时间窗: 24 hrs
The Capnostream is a portable CO2 monitor with a pulse oximetry module to measure and record SpO2 and heart rate and provides waveform patterns for respratory rate and EtCO2 measurement.
次要结局
未报告次要终点
研究者
Brendan Carvalho
Principle Investigator
Stanford University