Comparison of Intraperitoneal instillation of Bupivacaine with Magnesium sulphate versus Intravenous analgesics drugs for post operative pain relief after Laparoscopic cholecystectomy - A Randomized controlled study .
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- To compare post operative pain in laparoscopic cholecystectomy patients who will receive intravenous (IV) analgesics drugs versus those who will receive intraperitoneal Bupivacaine with Magnesium sulphate.
研究概览
简要总结
In this study , 52 patients aged between 20yrs to 60 yrs undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups for comparions of post -op pain relief after laparoscopic cholecystectomy . in one group patient will be given intraperitoneal instillation of bupivacaine with magnesium sulphate ,while in other group patient will receive intravenous analgesic agents for post operative pain.
Measuring indicator : NRS NUMERIC RATING SCALE
RAMSAY SEDATION SCALE
TIME FOR NEED FOR FIRST RESCUE ANALGESIA
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Double
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Inclusion Criteria
- •Patients undergoing elective laparoscopic cholecystectomy,
- •Patients of ASA grade 1 and 2 and
- •Patients aged between 20 to 60 years.
排除标准
- •Exclusion Criteria
- •Patient who will give negative informed consent .
- •Patients with allergy to the study drugs (MgSO4, Bupivacaine ,Paracetamol)
- •Chronic alcoholics,
- •Patients with heart block or renal failure .
- •Patients with peritoneal drain after surgery.
- •Patients treated with calcium channel blockers.
结局指标
主要结局
To compare post operative pain in laparoscopic cholecystectomy patients who will receive intravenous (IV) analgesics drugs versus those who will receive intraperitoneal Bupivacaine with Magnesium sulphate.
时间窗: AT 30 mins, 1 hour, 2 hour, 3 hour,6 hour, 12hour, 24hour
次要结局
- To assess changes in hemodynamic response and any adverse effects.(30 mins, 1hour, 2hour,3hour, 6 hour, 12 hour ,24 hour)
研究者
Dr Kajal
Heritage institute of medical sciences