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临床试验/NCT07539714
NCT07539714进行中(未招募)不适用

Heat Acclimation and Innovative Cooling Systems: Optimizing Athletic Performance and Reducing Heat-Induced Performance Impairments in Hot Environments Under Climate Change Conditions

Kaohsiung Medical University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年2月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
30
试验地点
1
主要终点
Heart Rate

研究概览

简要总结

This project investigates the effectiveness of pre-exercise active cooling using a temperature-controlled cooling vest in reducing heat-related physiological strain during endurance-type aerobic exercise in non-regularly trained ("weekend") athletes under hot and humid environmental conditions. Because these individuals often lack sufficient heat-acclimation training, they are at increased risk of excessive thermal stress, cardiovascular overload, and heat-related disorders during prolonged exercise.

Using a controlled laboratory design, participants will perform moderate-intensity endurance exercise in a simulated hot environment, with or without pre-cooling intervention. Peripheral circulation and thermoregulatory responses will be assessed through laser Doppler flowmetry based skin blood-flow analysis and infrared thermography, alongside heart rate and perceived exertion measures.

The study aims to clarify how active pre-cooling influences vascular regulation, sympathetic activity, skin temperature distribution, and exercise tolerance, and to evaluate its potential as a practical, non-fatiguing alternative to heat-acclimation training. The findings are expected to provide evidence-based guidance for reducing heat strain and improving exercise safety and comfort in recreational endurance athletes exercising in hot climates.

详细描述

The primary aim of this study is to investigate the effects of pre-exercise active cooling using a temperature-controlled vest on peripheral vascular regulation mechanisms in non-regular endurance exercisers under hot environmental conditions. Specifically, this study seeks to quantify how pre-cooling modulates skin blood-flow dynamics, sympathetic nervous system activity, endothelial function, and myogenic vascular control, as assessed through frequency-domain analysis of laser Doppler flowmetry signals, before and after endurance-type aerobic exercise. By characterizing these microcirculatory responses alongside changes in skin-surface temperature measured via infrared thermography, the study aims to elucidate the physiological pathways through which active pre-cooling attenuates thermal strain and cardiovascular load during exercise in the heat.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Factorial
主要目的
Basic Science
盲法
None

入排标准

年龄范围
20 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Age 20-50 years.
  • In the past 6 months, endurance exercise less than three times per week, 40-60 min each session.
  • No cardiovascular, metabolic (e.g., diabetes), or neurological disorders, and no diseases affecting vascular regulation.
  • No medication affecting vascular tone within the last 3 months.
  • No major musculoskeletal injuries or disorders affecting performance within the last 3 months.

排除标准

  • • Diabetes, hypertension, or peripheral vascular disease.
  • Long-term work in hot environments.
  • BMI > 30 kg/m², smoking, or heavy alcohol use.
  • Allergic reactions triggered by heat or cold (e.g., hives).

研究组 & 干预措施

Arm 1: Pre-Cooling with TEC Vest

Experimental

Arm 1: Pre-Cooling with TEC Vest

Participants receive pre-cooling using a temperature-controlled cooling vest (tec) for 30 mins prior to the exercise trial.

干预措施: TEC Vest (Device)

No Pre-Cooling (Without Vest)

Experimental

Arm 2: No Pre-Cooling

Participants complete the same exercise trial without any cooling intervention (no vest).

干预措施: No Pre-Cooling (Without Vest) (Other)

Pre-Cooling with Water Cooled Vest

Experimental

Pre-Cooling with Water Cooled Vest

Participants receive pre-cooling using a water cooled vest for 30 mins prior to the exercise trial.

干预措施: Water Cooled Vest (Device)

结局指标

主要结局

Heart Rate

时间窗: During a single laboratory visit lasting approx. 40 minutes: baseline immediately before the pre cooling period,immediately after 30 minutes of pre cooling,immediately after the 5 minute exercise bout, and immediately after the 5 minute seated cool down.

Temperature

时间窗: During a single laboratory visit lasting approx.40 minutes: baseline immediately before the pre cooling period, immediately after 30 minutes of pre cooling,immediately after the 5 minute exercise bout, and immediately after the 5 minute seated cool down.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ayesha Areeba

Principal Investigator

Kaohsiung Medical University

研究点 (1)

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