Quantifying myocardial inflammation in acute rheumatic fever and rheumatic heart disease using Magnetic Resonance Imaging (MRI).

Monash University0 个研究点目标入组 185 人开始时间: 2021年10月26日最近更新: 2024年5月27日

适应症

试验速览

暂无简介。

•ARF group inclusion
•-Aged 8 to 35 years
•-Definite, probable or possible ARF based on the 2020 Australian criteria for ARF diagnosis
•Non-ARF inflammatory group inclusion
•-Aged 8 to 35 years
•-Acute inflammatory/infective condition
•Control group inclusion
•-Aged 8 to 35 years
•- Currently well/healthy

•ARF group exclusion criteria
•-Claustrophobia
•-Metal implant/object that precludes cardiac MRI
•-Pregnant or breastfeeding women
•Non-ARF inflammatory group exclusion criteria
•-Probable ARF
•-Any major criteria for ARF
•-Chest pain
•-Signs/symptoms of heart failure
•-History of ARF/RHD
•-More than mild valvular disease on echocardiogram
•-Inflammatory condition commonly caused by streptococcal in which no alternate organism has been identified
•-Known recent/current streptococcal infection (within 6 months of enrolment)
•-Claustrophobia
•-Metal implant/object that precludes cardiac MRI
•-Pregnant or breastfeeding women
•Control group exclusion
•-Any infective or inflammatory condition
•-History of ARF/RHD
•-More than mild valvular disease on echocardiogram
•-Known streptococcal infection within 6 months of enrolment
•-Any major or minor criteria for ARF
•-Chest pain
•-Signs or symptoms of heart failure
•-Claustrophobia
•-Metal implant/object that precludes cardiac MRI
•-Pregnant or breastfeeding women

发起方