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临床试验/NCT03080662
NCT03080662Unknown不适用

Impact of Inspiratory Muscle Training on Daily Physical Activity (INAF)

Parc de Salut Mar2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2015年1月22日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
20
试验地点
2
主要终点
improvement of daily physical activity

研究概览

简要总结

The impact of the reduction of daily physical activity (DPA) in patients with COPD (chronic obstructive pulmonary disease) is a highly studied area, due to its impact on the quality of life and the clinical evolution of the disease . This fact has multifactorial components: its function is naturally diminished with time, and its effects on the loss of physical condition (decondition). However, dynamic hyperinflation and respiratory muscular dysfunction, especially in patients with more symptomatology, have been identified as those that have the most relevant factors that impact on daily physical activity Due to the detrimental effects of the pulmonary hyperinflation, the diaphragm is flatter and shorter, being in a position of mechanical disadvantage. This contributes to a reduced effort capacity and increase in the dyspnea of patients during daily activities.

Resistance training improves their exercise capacity and reduces dyspnea, however it does not improve inspiratory muscle strength. It is for this reason, that specific training of the inspiratory muscles, offers special interest in patients with decreased inspiratory muscle strength and pulmonary hyperinflation.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
45 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • To be eligible for the respiratory rehabilitation programme participants must have stable COPD (at least 4 weeks), inspiratory muscle weakness (PImax <70%) and pulmonary hyperinflation (TLC > 120%). Patient that have signed inform consent.

排除标准

  • Hospitalization within the previous 14 days
  • Current participation in rehabilitation program,
  • Locomotor or neurological condition or disability limiting the ability to perform exercise,
  • Lung transplantation or lung volume reduction surgery foreseen within 1 month after discharge.

结局指标

主要结局

improvement of daily physical activity

时间窗: Baseline and 5 weeks

Change From Baseline at least 10% moderate to vigorous daily physical activity measured by accelerometer

次要结局

未报告次要终点

研究者

发起方
Parc de Salut Mar
申办方类型
Other
责任方
Principal Investigator
主要研究者

Diego Agustín Rodríguez

Principal Investigator

Parc de Salut Mar

研究点 (2)

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