ACTRN12613000514707已完成未知
Effects of vitamin C and grape-seed polyphenols on blood pressure in treated hypertensive individuals
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 74
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 21 Years 至 75 Years（—）
- 性别
- All
入选标准
- •All individuals were taking one or more antihypertensive drugs for 3 months, had a mean 24-h ambulatory systolic BP of 125 mmHg and at least one additional cardiovascular disease (CVD) risk factor. Risk factors included previous coronary or cerebrovascular event > 6 months, hyperlipidaemia (total cholesterol > 6 mmol/l), use of lipid-lowering therapy, or smoking > 5 cigarettes/day. All volunteers ceased any vitamin, fish oil or antioxidant supplements for at least 3 weeks prior to study entry. All usual medication was taken as prescribed on the morning of each visit and maintained for the duration of the trial.
排除标准
- •Exclusion criteria included: previous coronary or cerebrovascular event 6 months, heart failure or unstable disease, premenopausal, use of nitrate medication, use of oral contraceptive, body mass index > 35 kg/m2, diabetes mellitus, fasting glucose 7 mmol/l, or elevated serum creatinine (men > 110 mmol/l or women > 100 mmol/l). Individuals were asked to limit tea and coffee intake to 3 cups/day, and cease all red wine and commercial fruit juice for the duration of the study.
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