CTIS2023-504519-34-01招募中1 期
sing live vaccines to induce beneficial innate immune training and reduce systemic inflammation in COPD patients (COPD-LIVE)
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 65+（—）
- 性别
- All
入选标准
- •Must have specialist verified, spirometry-confirmed, COPD., Age > 40 years, Able to give informed consent
排除标准
- •Acute febrile ilness, Oral or intravenous corticosteroid at a dose =10 mg/day over 3 months, Cardiac arythmia, Blood dyscrasia, Known allergy to either the BCG or MMR vaccines or severe adverse effects during prior vaccination., Allergy to MMR vaccine components, neomycin or egg proteins., Known prior, active or latent infection with mycobacterium tuberculosis., Pregnancy or breastfeeding, Vaccination with a live vaccine within 4 weeks, Severe immunocompromisation (HIV-1 infection, organ- or bone marrow transplantation, chemotherapy, primary immune defect, anti-cytokine therapy, immunosuppressant treatment)., Active solid or non-solid malignancy or lymphona within 2 years, excluding basal cell carcinoma
研究者
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