Comorbidities and Risk Score for Severity and Outcome in Patients With Infection by SARS-CoV-2.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4,555
- 试验地点
- 5
- 主要终点
- Mortality up to 3 months from admission
研究概览
简要总结
Retrospective multi-center cohort study. Consecutive patients hospitalized for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) up to October 2020 will be included. Patients are followed until discharge from hospital or death.
详细描述
Background
A virus causing clusters of severe pneumonia was first detected in the city of Wuhan, China, in December 2019.
This pathogen was designated as SARS-CoV-2. Although of probable zoonotic origin, human-to-human transmission has rapidly fuelled the spread of SARS-CoV-2 infection globally.
On February 20th, the first case of locally acquired SARS-CoV-2 infection was diagnosed in Northern Italy in a critically ill, hospitalized young man with no travel history to known areas of viral circulation or link to a probable or confirmed coronavirus infectious disease 2019 (COVID-19) case. Prior to this date, only three cases of COVID-19 had been reported in Central Italy, all with a travel history to Wuhan. Following this unexpected finding, case counts, and death tolls has increased rapidly in the country with a total of 192,994 confirmed cases and 25,969 deaths as of 24 April 2020.
Study rationale
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Mortality up to 3 months from admission
时间窗: Until study completion, an average of 1 year
Description of the mortality patients up to 3 months from admission
In-hospital mortality
时间窗: Until study completion, an average of 1 year
Description of the hospital mortality caused by the COVID19 disease
次要结局
- Admission to Intensive care unit (ICU)(Until study completion, an average of 1 year)
- Correlation between admission to ICU and in-hospital mortality(Until study completion, an average of 1 year)
- Complications occurred during the hospital course(Until study completion, an average of 1 year)