Impact of Circadian Misalignment on Insulin Sensitivity - Circadian misalignment and insulin sensitivity

niversiteit Maastricht0 个研究点目标入组 17 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

Trial is onging in other countries

•* Caucasian
•* Healthy (as determined by dependent physician based on medical questionnaire)
•* Age: 18-35 years
•* Normal BMI (18-25 kg/m2)
•* Regular sleeping time (normally 7 - 9h daily)
•* Habitual bedtime at 11 PM ± 2 hours

•* Extreme early bird or extreme night person (score *30 or *70 on MEQ-SA questionnaire)
•* Heavily varying sleep-wake rhythm
•* Shiftwork during last 3 months
•* Travel across >1 time zone in the last 3 months
•* Engagement in exercise > 3 hours total per week
•* Using > 400mg caffeine daily (more than 4 coffee or energy drink)
•* Unstable body weight (weight gain or loss > 3kg in the last 3 months)
•* Significant food allergies/intolerance (seriously hampering study meals)
•* Participation in another biomedical study within 1 month before the first study visit, which would possibly hamper our study results.
•* Claustrophobia (Subjects will see the respiration chamber, in which they will reside, during the screening visit).
•* Medication use known to hamper subject*s safety during the study procedures or to interfere with study results (as determined by responsible physician)
•* Subjects who intend to donate blood during the intervention or subjects who have donated blood less than three months before the start of the intervention.
•* Any contra-indication to the VitalSense telemetric pill.
•* Any acute condition, exacerbation of chronic condition, or medical history that would in the investigator*s opinion interfere with the study

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