ISRCTN10049430进行中（未招募）Unknown
The impact of Adverse Childhood Experiences on sensory thresholds in adults living with Multimorbidity And chronic Pain; a feasibility study (the ACE-MAP study)
niversity of Dundee0 个研究点目标入组 40 人开始时间: 2024年7月3日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •Four groups of participants aged =18 years old are eligible for recruitment:
- •1. Chronic pain with multimorbidity
- •1.1. Has =1 of the LTCs listed below
- •1.2. Has a diagnosis of chronic pain AND/OR has had persistent or recurring pain lasting >3 months
- •2. Chronic pain without multimorbidity
- •2.1. Has a diagnosis of chronic pain AND/OR has had persistent or recurring pain lasting >3 months
- •3. Multimorbidity without chronic pain
- •3.1 Has =2 of the LTCs listed below
- •4. Healthy volunteer controls
- •List of long-term conditions (LTCs):
- •Cardiovascular disease: stroke, coronary artery disease, heart failure, peripheral artery disease, heart valve disorders, arrhythmia, venous thromboembolic disease, aneurysm, hypertension (treated and untreated).
- •Metabolic and endocrine disease: diabetes, Addison’s disease, cystic fibrosis, thyroid disorders.
- •Respiratory disease: chronic obstructive pulmonary disease, asthma, bronchiectasis.
- •Neurological disease: Parkinson’s disease, epilepsy, multiple sclerosis, paralysis, transient ischaemic attack, peripheral neuropathy.
- •Cancer: solid organ cancers, haematological cancers, metastatic cancers, melanoma, benign cerebral tumours that cause disability.
- •Mental and behavioural disorder: dementia, schizophrenia, depression, anxiety, bipolar disorder, drug or alcohol misuse, eating disorder, autism, post-traumatic stress disorder.
- •Musculoskeletal disease: connective tissue disease, osteoarthritis, long-term musculoskeletal problems due to injury, osteoporosis, gout.
- •Digestive disease: chronic liver disease, inflammatory bowel disease, chronic pancreatic disease, peptic ulcer.
- •Urogenital disorder: chronic kidney disease, end-stage kidney disease, endometriosis, chronic urinary tract infection.
- •Haematological disorder: anaemia (including pernicious anaemia and sickle cell anaemia).
- •Eye disease: vision impairment that cannot be corrected.
- •Ear disease: a hearing impairment that cannot be corrected, Meniere’s disease.
- •Infectious disease: human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), chronic Lyme disease, tuberculosis, post-acute Covid-19.
- •Congenital disease: congenital disease or chromosomal abnormalities.
排除标准
- •1. Unable to read or speak English to a sufficient standard to complete questionnaires or to follow instructions for sensory tests,
- •2. Lacks the capacity to consent to participate in the study
- •3. Chronic pain without multimorbidity: Has =1 of the LTCs
- •4. Multimorbidity without chronic pain: Has a diagnosis of chronic pain AND/OR has had persistent or recurring pain lasting >3 months
- •5. Controls: Has =2 of the LTCs; A diagnosis of chronic pain AND/OR has had persistent or recurring pain lasting >3 months
研究者
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