The influence of dance training and strenght / endurance training on cognitive functions and the plasticity of the brain in senior citizens with an increased vascular risk - HIRNaktiv2

niversitätsMedizin Mannheim0 个研究点目标入组 90 人开始时间: 2016年9月15日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. age = 60 years
•2. retired (working < 10 hours / week)
•3. able to consent
•4. no regular physical activity before study inclusion
•5. willingness and availability to participate in training during the 12-month period regularly
•6. German as native language
•7. evidence of a relevant small vessel disease (Fazekas score 1 or higher)

•1. contraindication against magnetic resonance imaging (cardiac pace maker, metal implants, claustrophobia)
•2. history of a neurological disease with functional impairment
•3. history of a psychiatric disease with functional impairment
•4. diagnosis of a dementia or a cognitive impairment relevant for daily life
•5. malignancy, life expectancy < 12 months
•6. clinically significant cardiac disease, e.g. insufficiency NYHA III / IV, cardiac infarction within six weeks of inclusion, unsuited for sports
•7. clinically significant pulmonary disease, e.g. COPD III / IV
•8. planned surgical procedure during 12 month study intervention
•9. visual or hearing impairment, interfering with neuropsychological testing or fMRI
•10. intake of neuroleptics or anti-dementia drugs
•11. MoCA = 20
•12. MRI evidence of an intracranial hemorrhage, a cortical infarction, a space-occupying lesion, white matter lesion mimics

发起方

niversitätsMedizin Mannheim