ISRCTN10348278进行中（未招募）Unknown
Studying retinal structure with adaptive optics and function with multifocal electroretinogram
ewcastle upon Tyne Hospitals NHS Foundation Trust0 个研究点目标入组 40 人开始时间: 2023年11月9日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Other
入排标准
- 性别
- All
入选标准
- •1. Control
- •1.1. Adult between ages of 18 – 80 years old
- •1.2. Capable of performing all of the tests in the study procedures
- •1.3. Able to give informed consent to all of the procedures.
- •2. Late-onset retinal degeneration
- •2.1. Adult between ages of 18 – 80 years old
- •2.2. Capable of performing all of the tests in the study procedures
- •2.3. Able to give informed consent to all of the procedures
- •2.4. Have a confirmed genetic diagnosis of L-ORD
排除标准
- •1. Healthy control
- •1.1. Younger than 18 and older than 80 years old
- •1.2. Inability of participant to provide informed consent
- •1.3. Withdrawal of consent
- •1.4. BCVA of less than 6/12 in either eye
- •1.5. Participants with a spherical equivalent of greater than 4 dioptres or astigmatism greater than 2 dioptres
- •1.6. Taking any medication that can affect retinal function (e.g. Hydroxychloroquine, Deferasirox, Vigabatrin).
- •1.7. Known to have any ocular condition that will affect test results/ability to test:
- •1.7.1. Inherited retinal condition
- •1.7.2. Glaucoma
- •1.7.3. Age related macular degeneration
- •1.7.4. Amblyopia
- •1.7.5. Nystagmus
- •1.7.6. Corneal or other media opacity
- •1.8. Known to have any medical condition that will affect test results/ability to test:
- •1.8.1. Epilepsy
- •1.8.2. Raised intracranial pressure
- •1.8.3. Multiple sclerosis.
- •2. Late-onset retinal degeneration
- •2.1. Younger than 18 and older than 80 years old
- •2.2. Inability of participant to provide informed consent
- •2.3. Withdrawal of consent
- •2.4. Participants with a spherical equivalent of greater than 4 dioptres or astigmatism greater than 2 dioptres
- •2.5. Have loss of sufficient retinal structure to image (absent or substantially disrupted ellipsoid zone on SD-OCT)
- •2.6. Taking any medication that can affect retinal function (e.g. Hydroxychloroquine, Deferasirox, Vigabatrin)
- •2.7. Known to have any ocular condition that will affect test results/ability to test:
- •2.7.1. Nystagmus
- •2.7.2. Corneal or other media opacity
- •2.8. Known to have any medical condition that will affect test results/ability to test:
- •2.8.1. Epilepsy
- •2.8.2. Raised intracranial pressure
- •2.8.3. Multiple sclerosis.
研究者
相似试验
招募中
不适用
Observation study of the retina by Adaptive Optics Scanning Laser Ophthalmoscopy (AO-SLO)Retinal disease , healthy peopleJPRN-UMIN000015299Okayama University Hospital200
已完成
不适用
Retinal Imaging by Adaptive Optics in Healthy Eyes and During Retinal and General DiseasesRetinal DystrophiesArterial HypertensionTraumatic RetinopathyToxic RetinopathiesAge-related Macular DegenerationDiabetesNCT01546181Institut National de la Santé Et de la Recherche Médicale, France256
招募中
不适用
Examination of eye diseases with adaptive optics scanning laser ophthalmoscopyDiabetic retinopathy, age-related macular degeneration, retinitis pigmentosa, the other retinal diseasesJPRN-UMIN000016897Kyushu University220
招募中
不适用
Adaptive Optics Retinal ImagingGlaucoma, Primary Open AngleNCT05370287Food and Drug Administration (FDA)150
已完成
不适用
Adaptive Optics (AO) Analysis of Retinal Arteries in Patients With Recent Stroke (STROKAO)StrokeNCT04712747Fondation Ophtalmologique Adolphe de Rothschild91