Effect of Cold and Warm Enteral Feeding on Gastric Emptying in Adult Intensive Care Patients: A Cross-Over Study
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Gastric volume measured by ultrasonography at 60, 90, 120, 180, 240, 360, and 480 minutes after administration of cold and warm enteral feeding.
研究概览
简要总结
In critically ill patients receiving enteral nutrition in the intensive care unit, the functional capacity of the gastrointestinal system can be significantly influenced by the mode of nutritional support. The temperature of enteral feeding may exert potential effects on gastric emptying, intestinal motility, and nutrient absorption. However, the existing literature on the impact of feeding temperature is limited, and randomized or cross-over controlled studies directly comparing warm and cold enteral feeding are scarce. This study aims to systematically evaluate the effects of enteral feeding temperature on feeding tolerance (vomiting and aspiration), gastric emptying rate (gastric residual volume), and the incidence of diarrhea, thereby providing evidence to inform clinical practice.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 years or older
- •Expected length of stay in the intensive care unit of at least 96 hours
- •Patients receiving enteral nutrition via a nasogastric tube
- •Absence of ileus or active gastrointestinal bleeding
排除标准
- •Patients younger than 18 years of age
- •Use of high-dose opioids known to affect gastrointestinal motility
- •Patients receiving parenteral nutrition
- •Known gastrointestinal diseases or a history of gastrointestinal surgery
- •Patients with acute intracranial events will not be included in the study
研究组 & 干预措施
Cold Enteral Feeding
干预措施: enteral nutrition (Dietary Supplement)
Warm Enteral feeding
干预措施: enteral nutrition (Dietary Supplement)
结局指标
主要结局
Gastric volume measured by ultrasonography at 60, 90, 120, 180, 240, 360, and 480 minutes after administration of cold and warm enteral feeding.
时间窗: Baseline (0 minutes) and up to 480 minutes after enteral feeding
次要结局
未报告次要终点
研究者
Ilkay Ceylan
Associate proffesor
Bursa Yuksek Ihtisas Training and Research Hospital