IRCT20100101002950N7招募中2 期
Evaluation of the efficacy of oral curcumin on recurrency and number of complex aphthous lesions in the patients referred to the Oral and maxillofacial medicine Department of Guilan Dental School in 2021-2022
Rasht University of Medical Sciences0 个研究点目标入组 15 人开始时间: 待定最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 15
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 years 至 60 years（—）
- 性别
- All
入选标准
- •Patients between the ages of 20 and 60 years
- •Complex aphthous ulcers, which include: a number of painful aphthous lesions on the oral mucosa that appear intermittently and heal slowly;
- •Created in less than 72 hours
排除标准
- •Patients taking topical medication to treat the aphthous in the last two weeks or taking systemic medication in the last one month
- •Patients with systemic diseases such as intestinal and gastric diseases (Crohn's and ulcerative colitis), Behcet's disease, Reiter's syndrome and gallstones
- •Patients with anxiety disorders
- •Patients with bracets
- •Pregnant and lactating women
- •Patients with a history of alcohol and drug use
- •Patients treated with immunosuppressants, chemotherapy, and immunomodulatory drugs over the past year
- •History of allergies to plant compounds, including turmeric
- •High liver enzymes
- •Use of anticoagulants or antiplatelets (curcumin has an inhibitory effect on platelet aggregation) such as Warfarin, Aspirin, Clopidogrel, Epixaban, Rivaroxaban, Heparin and Enoxaparin
- •History of gastric ulcer and duodenal ulcer
- •Patients with inadequate literacy who do not understand the consent form
研究者
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