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临床试验/NCT06873295
NCT06873295已完成不适用

Evaluation of the Management Strategy for Acute Cholecystitis in the Digestive Surgery Department and Geriatric Intraoperative Unit in Subjects Over and Under 75 Years of Age

Centre Hospitalier Universitaire de Nīmes1 个研究点 分布在 1 个国家目标入组 424 人开始时间: 2023年3月22日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
424
试验地点
1
主要终点
Rate of patients with an initial cold cholecystectomy strategy who did not undergo surgery, died or underwent emergency surgery

研究概览

简要总结

The management of these often frail elderly patients, with more comorbidities and declining functional capacities, is more complex and justifies a specific, tailored approach.

Age is also associated with an increasing prevalence of gallstones. The disadvantages of "cold" surgery (longer hospital stay, higher cost, risk of disease recurrence in the interim, difficult surgery with more scar tissue due to repeated inflammation) have to be weighed against the high operative risk in the case of emergency surgery, leading to strict criteria for early cholecystectomy.

These criteria are rarely met in geriatric patients, who thus enter a hospital cycle whose impact on morbidity and mortality, as well as on loss of autonomy, has been demonstrated in this population. What's more, the deteriorating general condition of frail elderly patients means that a number of them end up being definitively rejected for surgery, despite an initial strategy of cold cholecystectomy.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
19 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients over 18 years of age.
  • •Diagnosis of acute cholecystitis.
  • •Hospitalization in the digestive surgery department and geriatric perioperative unit of Nîmes University Hospital.

排除标准

  • •Patients under 18 years of age.
  • •Opposition of the patient to his inclusion in the study after sending the letter of information and non-opposition.

结局指标

主要结局

Rate of patients with an initial cold cholecystectomy strategy who did not undergo surgery, died or underwent emergency surgery

时间窗: Up to 6 months, from date of first collection to date of end of collection

Percentage

次要结局

未报告次要终点

研究者

发起方
Centre Hospitalier Universitaire de Nīmes
申办方类型
Other
责任方
Sponsor

研究点 (1)

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