Dismantling the Components and Dosing of CBT for Co-Occurring Disorders
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 2
- 主要终点
- Number of Participants That Relapsed to Drinking at 4 Months
研究概览
简要总结
The purpose of this study is to establish a brief CBT intervention that can largely, if not fully eliminate the deleterious effect of common co-occurring anxiety disorders on alcohol use disorder treatment outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnostic and Statistical Manual IV diagnosis of panic disorder, generalized anxiety disorder, and/or social anxiety disorder within the past 30 days;
- •inpatient treatment at Lodging Plus primarily for alcohol (vs. other drug) dependence
- •alcohol use in the 30 days preceding the study
- •ability to provide informed consent
- •minimum of a sixth grade reading level (deemed necessary to complete study materials);
- •willingness to provide contact information to confirm study follow-up appointments
- •lives within proximity to the Twin Cities (e.g., within about an hour's drive) for the purpose attending follow-up visits
排除标准
- •lifetime history of psychosis or mania by history
- •cognitive or physical impairment that precludes study participation
- •currently and seriously suicidal (i.e., plan and intent)
结局指标
主要结局
Number of Participants That Relapsed to Drinking at 4 Months
时间窗: 4 month follow-up
Relapse status will be assessed using categorical relapse status (yes vs. no). Count is of those who relapsed
Number of Drinking Days in 4 Months Post Treatment
时间窗: 4-months
Negative binomial regression with offset for possible drinking days exposure in 4 months post treatment
Number of Standard Drinks Per Drinking Day
时间窗: 4 months
Drinks per drinking day among those who relapsed by 4 months. Standard Drink is defined as 12oz beer, 4ox wine, 3oz fortified wine, 1oz hard liquor
次要结局
- Number of Participants Who Met SCID-IV Criteria for Alcohol Dependence at 4 Months(4 months)
- Number of Participants Who Relapsed to Hazardous Drinking(4 months)