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临床试验/NCT02046785
NCT02046785Unknown不适用

Comparison of CVP Values , ΔPP and Echocardiographic at Different Angles Headwaters Before and After Volume Challenge

Federal University of Uberlandia2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2013年4月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
30
试验地点
2
主要终点
Different Backrest position's effect on CVP, CO and ∆PP measures

研究概览

简要总结

The purpose of this study is to determine whether hemodynamic measures vary in angles bedside before and after volume challenge.

详细描述

  • Check if values of central venous pressure (CVP), pulse pressure variation (Δpp), heart rate (HR), mean arterial pressure ((PAM) vary in different angles headboards
  • Compare values of CVP, Δpp, HR and MAP as predictors of blood volume after supply of 500 ml of 0.9% saline solution.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Being in circulatory shock and have at least one of the following criteria to identify loss of tissue perfusion: systolic blood pressure <90 mmHg or need for vasoactive drugs, urine output below 0.5 ml / kg / h.
  • Being under sedation, assessed by the scale of Richmond agitation and sedation (RASS) -5, mechanically ventilated in volume control mode with tidal volume between 8 to 12 ml/kg, PEEP to 8 cm H2O.
  • Tue signing the informed consent by legal guardian.

排除标准

  • Presence cardiac arrhythmias.
  • Presence of abdominal or thoracic trauma.
  • Contraindication for passive elevation of the members.
  • Hypoxia significant PaO2/FiO2 < or equal 100.

结局指标

主要结局

Different Backrest position's effect on CVP, CO and ∆PP measures

时间窗: Data collection was performed at admission or within 10 days of hospitalization between September 2013 and February 2014.

次要结局

未报告次要终点

研究者

发起方
Federal University of Uberlandia
申办方类型
Other
责任方
Principal Investigator
主要研究者

Rosangela de Oliveira Felice

nursing specialist

Federal University of Uberlandia

研究点 (2)

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