A Randomized Controlled Trial Comparing Continuous Sciatic Nerve Block to Single Shot Sciatic Nerve Block
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- Temporary Neurologic Symptoms Between Groups
研究概览
简要总结
The purpose of this study is to compare the incidence of postoperative symptoms of neurologic injury after a single shot infragluteal-parabiceps sciatic nerve block versus a continuous infragluteal-parabiceps sciatic nerve catheter.
详细描述
There are a limited number of prospective studies in the literature examining the risk of neurologic injury and symptoms after sciatic nerve blocks. The incidence of transient neurological symptoms after a continuous catheter is not well reported.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients ( ≥18 and ≤ 80) who are scheduled to undergo elective scheduled foot surgery and agreed to receive a sciatic nerve catheter as a part of their postoperative pain management. this study.
排除标准
- •history of hemostatic abnormalities
- •chronic pain syndrome
- •a foot deformity restricting normal foot movement
- •severe liver or renal disease
- •a preexisting neurologic disorder
- •patient refusal to participate
- •the presence of language barrier that prohibits proper communication with patient.
研究组 & 干预措施
Single Shot Sciatic Nerve Block
Single shot sciatic nerve blocks will be performed by resident trainees supervised by faculty. Bupivacaine 0.625% with epinephrine 1:300,000 will be injected incrementally in 3-ml aliquots to a total volume of 0.4 ml/kg (minimum, 20 ml; maximum, 35 ml).
干预措施: Bupivacaine (Drug)
Continuous Sciatic Nerve Block
Continuous sciatic nerve block catheters will be performed using an insulated needle connected to the negative lead of a constant current nerve stimulator. The catheter will be advanced under ultrasound guidance. A test dose of 1.5% lidocaine with epinephrine will be injected to confirm catheter placement. All subjects will receive a portable pump that will infuse 0.2% ropivacaine 5 ml/hr with a 5 ml bolus/hr. The subjects will follow standard protocol discharge instructions in regards to removing the catheter themselves.
干预措施: Ropivacaine (Drug)
结局指标
主要结局
Temporary Neurologic Symptoms Between Groups
时间窗: 1 month
Temporary neurologic symptoms between groups; muscle weakness of either foot dorsiflexion and plantar flexion
次要结局
- Pain Control(72 hrs)
- Participant Satisfaction With Anesthesia(24 hours)
研究者
Antoun Nader
Professor of Anesthesiology
Northwestern University