CTRI/2021/12/038917招募中未知
To Study the Safety and Efficacy of Simvastatin in Patients With Hepatopulmonary Syndrome in Cirrhosis- A Double Blind Randomized Controlled Trial-Superiority Trial
试验速览
- 阶段
- 未知
- 状态
- 招募中
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1) Diagnosed case of Hepato-pulmonary syndrome AaPO2 > 15 mm Hg on standing room air arterial blood gas (ABG). PaO2 <80 mmHg for clinical HPS between 18-70 years of years
- •2) Child A/B cirrhosis, Child C with CTP score of
- •more than equals to 10
- •3) Patient with no liver transplant option
排除标准
- •1) Child-C cirrhosis CTP >10
- •2) Very Severe HPS
- •3) Acute-on-chronic liver failure
- •4) Thrombosis of splenoportal axis
- •5) Hepatocellular carcinoma
- •6) Renal dysfunction
- •7) Patients intolerant to beta blockers (history of hypotension or bradycardia)
- •8) Contraindication for beta-blockers (history of chronic obstructive pulmonary disease, atrioventricular block)
- •9) Pregnant females
- •10) Refusal to participate in the study
- •11) Hepatic Hydrothorax
研究者
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