An Analysis of the Efficacy of a Pre-Emptive Multimodal Pain Regimen in Reducing Acute Post-Operative Pain and Narcotic Pain Medication Requirements in Spine Surgery
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Visual Analogue Scale (VAS) for Pain
研究概览
简要总结
The aim of this study is to investigate the hypothesis that multimodal pain regimen (consisting of acetaminophen, celecoxib, gabapentin, and oxycodone) administered pre-operatively before elective spine surgery significantly decreases acute pain post-operatively as well as decreasing requirements of post-op opioids for pain control in PACU as compared to patients undergoing elective spine surgery without a pre-operative pain regimen.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Undergoing elective spine surgery at NYU Winthrop
- •Age over 18 years
排除标准
- •History of neuromuscular disorders
- •History of inflammatory arthropathies
- •History of spine metastases or active cancer in spine
- •Medical History including any of the following: renal dysfunction, gastric ulcers, hepatic dysfunction, coagulopathic/bleeding disorders, prior adverse or allergic reactions to any of the medications in the study
- •Age less than 18 years
研究组 & 干预措施
Patients undergoing elective spine surgery
干预措施: Pre-op Multimodal analgesia (MMA) regimen + standard post-op oxycodone (Drug)
结局指标
主要结局
Visual Analogue Scale (VAS) for Pain
时间窗: 24 hours
VAS is a tool widely used to measure pain. A patient is asked to indicate his/her perceived pain intensity (most commonly) along a 100 mm horizontal line, and this rating is then measured from the left edge (=VAS score). The total score range is 0 (no pain) to 10 (worst pain imaginable); the higher the score, the worse the pain.
Opioid Sparing and Rescue Time
时间窗: 24 hours
Time interval from patient extubation to time when pain medication is first demanded in the PACU
次要结局
- Length of Stay in Hospital(Up to 12 days)