Clinical performance of Compass in the diagnosis of glaucoma: a comparison with Humphrey HFA.

CenterVue SpA0 个研究点目标入组 1,041 人开始时间: 2015年8月20日最近更新: 2023年9月26日

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2019 Results article in https://pubmed.ncbi.nlm.nih.gov/30114416/ results (added 01/09/2020) 2022 Results article in https://doi.org/10.3389/fmed.2022.923096 (added 12/09/2023) 2020 Results article in http://dx.doi.org/10.1136/bjophthalmol-2019-315070 (added 12/09/2023)

•Normal subjects:
•1. Age: 18 - 90 years old
•2. best corrected visual acuity > 0.8 (if <50 years old) or >6/10 (if >50 years old) in study eye
•3. Refraction -10D / +6D; astigmatism between - 2D and 2D
•4. Normal optic nerve head in both eyes (no evidence of excavation, rim thinning, notching, disc hemorrhages, RNFL thinning);
•5. IOP less than 21 mmHg in both eyes
•6. No ocular pathologies, trauma, surgeries (apart from uncomplicated cataract surgery) in both eyes
•7. Absence of pathologies that can affect visual field
•8. No use of drugs interfering with the correct execution of perimetry
•9. Should have at least two reliable VF exams (for example one HFA, one Compass)
•Glaucoma patients:
•1. Age: 18 - 90 years old
•2. Best corrected visual acuity > 0.8 (if <50 years old) or >6/10 (if >50 years old) in study eye;
•3. Refraction -10D / +6D; astigmatism between - 2D and 2D
•4. Glaucomatous optic nerve head in both eyes (according to the specialist opinion at ophthalmoscopy) and abnormal OCT (ONH and RNFL)
•5. Patients under anti-glaucoma therapy
•6. No ocular pathologies, trauma, surgeries (apart from uncomplicated cataract surgery) in both eyes
•7. Absence of pathologies that can affect visual field other than glaucoma
•8. No use of drugs interfering with the correct execution of perimetry or that would produce visual field loss
•9. Should have at least two reliable VF exams (for example one HFA, one Compass)

•Normal subjects:
•1. Age: <18 or >90 years old
•2. Best corrected visual acuity <= 0.8 (if <50 years old) or <=6/10 (if >50 years old) in study eye
•3. Refraction < -10D or >+6D; astigmatism between <- 2D or >2D
•4. Abnormal optic nerve head in both eyes ( evidence of excavation, rim thinning, notching, disc hemorrhages, RNFL thinning)
•5. IOP > 21 mmHg in both eyes
•6. Ocular pathologies, trauma, surgeries (apart from uncomplicated cataract surgery) in both eyes
•7. Presence of pathologies that can affect visual field
•8. Use of drugs interfering with the correct execution of perimetry
•9. Less than two reliable VF exams
•Glaucomatous subjects:
•1. Age: <18 or >90 years old
•2. Best corrected visual acuity <= 0.8 (if <50 years old) or <=6/10 (if >50 years old) in study eye
•3. Refraction < -10D or >+6D; astigmatism between <- 2D or >2D
•4. Normal optic nerve head in both eyes (according to the specialist opinion at ophthalmoscopy) and normal OCT (ONH and RNFL)
•5. Patient not under anti-glaucoma therapy
•6. Ocular pathologies, trauma, surgeries (apart from uncomplicated cataract surgery) in both eyes
•7. Presence of pathologies that can affect visual field other than glaucoma
•8. Use of drugs interfering with the correct execution of perimetry or that would produce visual field loss
•9. Less than two reliable VF exams (for example one HFA, one Compass)

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