Evaluation of Pressure Algometry in the Clinical Assessment of Acute Abdominal Pain in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 427
- 主要终点
- Appendicitis
研究概览
简要总结
In this retrospective observational case study, the investigators review the clinical experience with pressure-pain algometry in children with suspected appendicitis. The investigators hypothesized that algometry can discriminate children with appendicitis from children without appendicitis and aimed to determine the diagnostic accuracy of algometry, compared to ultrasound imaging and clinical assessment.
详细描述
As a retrospective cohort study, participants include all children referred with abdominal pain from January 2000 to June 2006 to one surgeon (R.P.) on the pediatric general surgery service at the Health Sciences Centre (HSC)-Children's Hospital in Winnipeg. The HSC-Children's Hospital is the only pediatric surgery centre within a radius of 600 km. All included participants have had acute abdominal pain ≤ 7 days, and suspected appendicitis based on standard history and physical exam. Standard appendicitis treatments were used: analgesia, antibiotics, operation. The Research Ethics Board of the University of Manitoba approved the study and reporting of the findings (H2003:104).
The investigators use standard clinical, laboratory, diagnostic imaging procedures for appendicitis diagnosis. The final diagnosis is defined by:
- pathology report indicating transmural inflammation, or
- from the surgeon's report when pathology was unavailable, or
- by discharge diagnosis in non-operated patients.
Appendix rupture is defined by the presence of pus and full-thickness perforation of the appendix wall or abscess formation at operation or on pathology examination. The appendix condition is classified as normal, non-perforated or perforated; all other pathologies at operation are recorded. Treatments, complications and morbidity are tabulated.
Clinical Measures
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 2 Years 至 17 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all children referred with abdominal pain from January 2000 to June 2006 to one surgeon on the pediatric general surgery service at the Health Sciences Centre (HSC)-Children's Hospital in Winnipeg.
排除标准
- •children with abdominal pain > 7 days
- •children with abdominal pain due to other surgical or medical conditions
结局指标
主要结局
Appendicitis
时间窗: within 1week
Diagnosis of appendicitis by pathology report if available.
Non-Appendicitis
时间窗: Within one (1) week
Diagnosis of non-appendicitis by observation only
Pressure-pain algometry
时间窗: Within one (1) week
Serial measurements taken before final management decision
次要结局
- Complications following appendectomy(For one (1) month following operation or observation.)
研究者
Ray Postuma
Professor of Surgery - retired
University of Manitoba
