NCT01562808已完成不适用
The Relationship Between D2 Occupancy and Change in Frontal Metabolism and Working Memory Induced by Aripiprazole
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Reaction time of correct response in N-back task
研究概览
简要总结
Dopamine receptor occupancy and brain metabolism were measured using positron emission tomography after the administration of aripiprazole. Working memory performance was also measured using N-back task.
The investigators explored the relationship between changes in brain metabolism and working memory performance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 19 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •healthy volunteers
- •right-handed
排除标准
- •any significant abnormality on routine lab
- •any psychiatric disease
结局指标
主要结局
Reaction time of correct response in N-back task
时间窗: 48 hrs after the administration of aripiprazole
次要结局
未报告次要终点
研究者
Jun Soo Kwon
Professor
Seoul National University Hospital
研究点 (2)
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