CTRI/2018/07/015039尚未招募未知
To evaluate the safety and feasibility of HLA-mismatched stem cell microtransplantation in relapsed and refractory acute myeloid leukemia (AML)patients who do not have matched sibling donor : A single arm prospective,interventional, pilot study â??
DEPARTMENT OF MEDICAL ONCOLOGY AIIMS0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Age 18-65 years
- •2. No 10/10 matched sibling and matched unrelated donor available
- •3. Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2, and estimated survival of at least 3 months
- •4. Patients must be able to understand and agree to sign an Institutional Review Board (IRB)-approved informed consent form
- •5)Patient has at least one medically fit first- or second-degree family member expected to be human leukocyte antigen (HLA) mismatched at 2-9/10 loci; in addition, the prospective donor is willing to voluntarily donate hematopoietic stem cells and sign consent forms
排除标准
- •1. Acute promyelocytic leukemia
- •2. Therapy related AML/ MDS-AML
- •3. Chronic myeloid leukemia in accelerated phase and blastic phase
- •4. Previous allogeneic or autologous HSCT or solid organ transplantation
研究者
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