Towards Developing a Perceptual Learning Treatment for Amblyopia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- Change of grating acuity
研究概览
简要总结
Objectives. To develop a new treatment for amblyopia using a perceptual learning approach.
Hypothesis to be tested. Our proposed experiments are designed to investigate whether practicing a grating detection task can improve vision in patients with amblyopia.
Design and subjects. A total of 36 patients with amblyopia will be randomized allocated into two intervention groups: Group 1, perceptual learning therapy. Group 2, occlusion therapy. A control group comprising of 18 subjects with normal vision will be recruited for comparison. A battery of tests will be used to assess a range of visual functions before and after the treatment intervention.
Study instruments. Grating acuity testing system
Interventions. We have established a clinical protocol for acuity training. On each trial, a properly oriented stimulus will be presented randomly at one of the four locations on a flat monitor screen. The visual task is to indicate the location of the stimulus. Participants will be required to undertake 20 one-hour sessions of training.
Main outcome measures. Resolution acuity, visual acuity, contrast sensitivity function
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 7 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Visual acuity in the amblyopic eye: 20/25 or worse
排除标准
- •Manifest eye disease & nystagmus
结局指标
主要结局
Change of grating acuity
时间窗: 20 hours
Grating acuity tests the participants' ability to resolve fine details. This study measures the change of grating acuity after 20 hours of vision training.
次要结局
- Change of visual acuity(20 hours)
- Change of contrast sensitivity(20 hours)
- Change of stereopsis(20 hours)