ACTRN12618000409279进行中（未招募）未知
The effect of enteral glycine on plasma glycine and muscle histopathology, structure and function in the critially ill
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 入组人数
- 29
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •a.Aged 18 years or over
- •b.Receiving invasive mechanical ventilation and expected to remain mechanically ventilated until the day after tomorrow
- •c.Arterial or central venous line in situ
- •d.Receiving or suitable to receive EN
- •e.Expected to be receiving EN in the ICU until at least the day after tomorrow
排除标准
- •a.Death during ICU admission deemed to be inevitable
- •b.Pregnancy
- •c.Lower limbs amputated
- •d.Spinal cord injury
- •e.Presented with primary neuromuscular pathology
- •f.Presented with disseminated cancer
- •g.Bleeding diathesis (corrected INR > 1.5 and/or APTT > 50), or receiving anticoagulants beyond that required for venous thromboembolism prophylaxis or antiplatelet drugs other than aspirin
- •h.Received > 72 hours of EN or PN during this ICU admission
- •i.Intolerant of EN (gastric residual volume > 300mL)
- •j.Already been admitted to ICU for > 96 hours during this hospitalization
- •k.Previously enrolled in this study
- •l.Requirement for specific nutritional therapy as determined by the treating doctor or dietitian
研究者
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